Sepsis Clinical Guide6.0 - App Store

Sepsis Clinical Guide now includes access the new ESCAVO Clinical Community, a forum where clinicians can exchange ideas, ask questions and collaborate on sepsis and other clinical topics.

Sepsis is a serious systemic infection that can quickly lead to circulatory shock, organ failure and death if inappropriately treated. In 2017, over 2 million people were admitted to US hospitals for sepsis (#1 cause of index admissions) at a total aggregate cost to the US healthcare system of $38.2 billion dollars (#1 most expensive condition), according to an AHRQ report. Over 270,000 people die of sepsis in the US every year, more than from prostate cancer, breast cancer and AIDS combined. Despite its large toll on public health, public awareness of this condition is poor and the quality of treatment is highly variable often due to delayed recognition and treatment.

In sepsis, time is of the essence. Successful treatment hinges on prompt recognition of symptoms, correct antibiotic administration, and hemodynamic stabilization. Lack of appropriate sepsis management knowledge at the bedside leads to delayed symptom recognition, serious complications, medical errors, increased treatment costs, and avoidable morbidity and mortality. For this reason, we created this app to provide busy health professionals with essential management information based on the latest practice guidelines in a format that is easily accessible at the point of care.

The Sepsis app was developed on the ESCAVO mobile publishing platform created specifically for mobile publishing of scientific content. The platform features an intuitive user interface, search, annotation and bookmarking functions, and calculator support. All content is extensively referenced and footnoted where appropriate.

Clinical topics covered in the Sepsis app include:
- Updated with the latest definitions, diagnostic criteria, and management guidelines including the 2016 Sepsis-3 definitions and the latest Surviving Sepsis Campaign (SSC) guidelines
- Epidemiology, risk factors and pathophysiology of sepsis and septic shock
- Common differentials and etiology, guidelines on performing appropriate H&P and workups
- Management of common causes including hospital-acquired pneumonia (HAP), ventilator-acquired pneumonia (VAP) and intra-abdominal infections
- Sepsis management bundles, early goal-directed therapy, hemodynamic management, adjunctive therapies, mechanical ventilation of sepsis-induced ARDS, and other essential management guidelines from the SSC and the American Thoracic Society (ATS)
- Antibiotic therapy including specific guidelines for the treatment of HAP from ATS and the Infectious Diseases Society of America (IDSA)
- Guidance on the prevention, recognition and treatment of Clostridium difficile based on the latest IDSA guidelines
- Information on the diagnosis and management of pediatric and neonatal sepsis including the management of pediatric fever, important differences from adult sepsis, management of sepsis-induced persistent pulmonary hypertension of the newborn (PPHN), empiric antibiotic treatment recommendations for GBS infections, interventions in pediatric septic shock, and other pediatric-specific information
- Important score calculators including the Sequential Organ Failure Assessment (SOFA), quick-SOFA, SIRS, APACHE II, Multiple Organ Dysfunction Score (MODS), the Simplified Acute Physiology Score (SAPS) II, National Early Warning Score (NEWS), the Clinical Pulmonary Infection (CPI) score, the Inferior Vena Cava Collapsibility Index, and others
- Drug administration information for the management of sepsis including antibacterial and antifungal antibiotics, the latest drugs for emerging multi-drug resistant organisms, adrenergic and other vasoactive agents, corticosteroids and diuretics
- Relevant COVID-19 management information

Recommended by:
- HealthTap.com
- MDLinx.com
- imedicalapps.com
- The ED Trauma Critical Care Blog (edtcc.com)

Version History - Bug fixes and performance enhancements 6.0 10/14/2023 Bug fixes & minor UI improvements 5.1 05/22/2023 - Complete app rebuild
- Major user interface and performance improvements 5.0 04/15/2023 - Software update and bug fixes 4.8 03/14/2022 - Bug fixes 4.7 03/13/2022 - Dark mode support
- Major software updates and bug fixes
- UI improvements 4.6 01/06/2022 - Minor bug fixes 4.5 08/27/2019 - New look, cleaner UI
- Lots of under the hood improvements and bug fixes 4.4 05/02/2019 - Optimized for iPhone XR, XS and XS Max
- Miscellaneous bug fixes 4.3 11/28/2018 - UI optimizations, bug fixes
- Preloaded recent content updates for faster startup 4.2 04/10/2018 - Extensive content update
- Bug fixes
- UI enhancements 4.1 03/16/2018 - Major code revision for improved stability
- iPhone X support
- Bug fixes and minor UI improvements
- Improved search function 4.0 01/09/2018 - Bug fixes
- Content updates
- Minor UI improvements 3.7 03/30/2016 - Bug fixes
- Ad support 3.6.0 05/17/2015 - 64-bit support
- Added content styling support
- Improved content style: colorful footnote/reference markers and links for better visibility
- Improved calculator UI 3.5.0 04/10/2015 - UI updates
- Link directly to PubMed abstracts from references
- One-touch add/delete bookmark from pages
- Footnote/reference/drug marker bug fixed
- Other bug fixes 3.4.0 07/14/2014 - Updated interface for iOS7
- Bug fixes 3.3.0 12/24/2013 - Internationalization support
- Spanish version for Spanish speaking locales 3.2.0 09/16/2013 - New look and graphics
- Annotation feature
- Editable tab bar
- iPad support
- Bug fixes and UI adjustments 3.1 08/09/2013 - New look and graphics
- Annotation feature
- Editable tab bar
- iPad support
- Bug fixes and UI adjustments 3.0 08/07/2013 - Added support for iOS6 and iPhone5
- Upgraded underlying framework, UI optimization, various bug fixes
- Added News feature that lets users optionally receive news items and other information on sepsis and relevant topics
- Added double-tap zoom in/out in slideshows
- Added support for bookmark migration between major releases
- Preloaded app with latest content for faster initial start 2.0 12/19/2012 Bug fixes related to image content updates 1.0.1 03/14/2012 1.0 09/27/2011